| Gene Information | |
|---|---|
| Gene Name | POLR2C |
| Organism | Homo sapiens (Human) |
| Gene Length | 275 |
| Protein Names | DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3) (RNA polymerase II subunit B3) (DNA-directed RNA polymerase II 33 kDa polypeptide) (RPB33) (DNA-directed RNA polymerase II subunit C) (RPB31) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000102978 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | P19387 |
| Gene Card | POLR2C |
| Uniprot ID | P19387 |
| Pfam | PF01000; PF01193 |
| In ASD | no |
| Allosteric Prediction | no (-0.193650855) |
| Ortholog in Animals | Alpaca_ POLR2C ( ortholog_one2one ) Dog_ POLR2C ( ortholog_one2one ) GuineaPig_ POLR2C ( ortholog_one2one ) Macaque_ POLR2C ( ortholog_one2one ) Mouse_ Polr2c ( ortholog_one2one ) Pig_ POLR2C ( ortholog_one2one ) Rat_ Polr2c ( ortholog_one2one ) Rabbit_ POLR2C ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | POLR1C, CRIPT |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.251286(Chimpanzee);NULL(Mouse);NULL(Rat);0.269470(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5IY6 (EM 7.20A ) 5IY7 (EM 8.60A ) 5IY8 (EM 7.90A ) 5IY9 (EM 6.30A ) 5IYA (EM 5.40A ) 5IYB (EM 3.90A ) 5IYC (EM 3.90A ) 5IYD (EM 3.90A ) 6DRD (EM 3.90A ) 6O9L (EM 7.20A ) 6XRE (EM 4.60A ) 7LBM (EM 4.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:9852112}. |
| Mouse PG classification | NA |
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