Gene Information
Gene NameHIP1R
OrganismHomo sapiens (Human)
Gene Length1068
Protein NamesHuntingtin-interacting protein 1-related protein (HIP1-related protein) (Huntingtin-interacting protein 12) (HIP-12)
Target NameNA
Target TypeNA
Gene Age1488 ( ENSG00000130787 )
Evolutionary StageEukaryota
AlphaFoldDBO75146
Gene CardHIP1R
Uniprot IDO75146
PfamPF07651; PF16515; PF01608
In ASDno
Allosteric Predictionno (-0.234626625)
Ortholog in AnimalsAlpaca_ HIP1R ( ortholog_one2one )
Dog_ HIP1R ( ortholog_one2one )
GuineaPig_ HIP1R ( ortholog_one2one )
Macaque_ HIP1R ( ortholog_one2one )
Mouse_ Hip1r ( ortholog_one2one )
Pig_ HIP1R ( ortholog_one2one )
Rat_ Hip1r ( ortholog_one2one )
OhnologsHIP1
ParalogsHIP1
TissueNA
Tissue SpecificityBrain, heart, kidney, pancreas, and liver, but not in lung or placenta.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.002369(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1R0D  (X-ray  1.90A 
DBSNP rs149504879  rs7972242  rs7972242  rs2271051  rs3736414 
Subcellular location [CC]Cytoplasm, perinuclear region. Endomembrane system. Cytoplasmic vesicle, clathrin-coated vesicle membrane. Note=Membrane-associated protein, mainly localized at the endocytic compartments and in the perinuclear region.
Mouse PG classificationNA
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