| Gene Information | |
|---|---|
| Gene Name | SFRP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 295 |
| Protein Names | Secreted frizzled-related protein 2 (FRP-2) (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000145423 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96HF1 |
| Gene Card | SFRP2 |
| Uniprot ID | Q96HF1 |
| Pfam | PF01392; PF01759 |
| In ASD | no |
| Allosteric Prediction | no (-0.896431998) |
| Ortholog in Animals | Alpaca_ SFRP2 ( ortholog_one2one ) Dog_ SFRP2 ( ortholog_one2one ) GuineaPig_ SFRP2 ( ortholog_one2one ) Macaque_ SFRP2 ( ortholog_one2one ) Mouse_ Sfrp2 ( ortholog_one2one ) Pig_ SFRP2 ( ortholog_one2one ) Rat_ Sfrp2 ( ortholog_one2one ) Rabbit_ SFRP2 ( ortholog_one2one ) |
| Ohnologs | SFRP1, SFRP5 |
| Paralogs | SFRP5, SFRP1, FZD5, FZD2, FZD10, FZD9, SFRP4, FZD7, FRZB, FZD6, FZD8, SMO, FZD1, FZD4, FZD3 |
| Tissue | NA |
| Tissue Specificity | Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon. {ECO:0000269|PubMed:9391078, ECO:0000269|PubMed:9642118}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs4643790 |
| Subcellular location [CC] | Secreted {ECO:0000250}. |
| Mouse PG classification | NA |
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