| Gene Information | |
|---|---|
| Gene Name | ZFP36L2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 494 |
| Protein Names | mRNA decay activator protein ZFP36L2 (Butyrate response factor 2) (EGF-response factor 2) (ERF-2) (TPA-induced sequence 11d) (Zinc finger protein 36, C3H1 type-like 2) (ZFP36-like 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000152518 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P47974 |
| Gene Card | ZFP36L2 |
| Uniprot ID | P47974 |
| Pfam | PF04553; PF00642 |
| In ASD | no |
| Allosteric Prediction | no (-0.360914261) |
| Ortholog in Animals | Alpaca_ ZFP36L2 ( ortholog_one2one ) Dog_ ZFP36L2 ( ortholog_one2one ) GuineaPig_ ZFP36L2 ( ortholog_one2one ) Macaque_ ZFP36L2 ( ortholog_one2one ) Mouse_ Zfp36l2 ( ortholog_one2one ) Pig_ ZFP36L2 ( ortholog_one2one ) Rat_ Zfp36l2 ( ortholog_one2one ) Rabbit_ ZFP36L2 ( ortholog_one2one ) |
| Ohnologs | ZFP36L1 |
| Paralogs | ZFP36, ZFP36L1 |
| Tissue | NA |
| Tissue Specificity | Expressed mainly in the basal epidermal layer, weakly in the suprabasal epidermal layers (PubMed:27182009). Expressed in epidermal keratinocytes (at protein level) (PubMed:27182009). {ECO:0000269|PubMed:27182009}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1RGO (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:P23949}. Cytoplasm {ECO:0000250|UniProtKB:P23949}. Note=Shuttles between the nucleus and the cytoplasm in a XPO1/CRM1-dependent manner. {ECO:0000250|UniProtKB:P23949}. |
| Mouse PG classification | NA |
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