Gene Information
Gene NameMARCKS
OrganismHomo sapiens (Human)
Gene Length332
Protein NamesMyristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL)
Target Namemyristoylated alanine-rich c-kinase substrate
Target TypeClinical trial target
Gene Age55 ( ENSG00000277443 )
Evolutionary StageVertebrata
AlphaFoldDBP29966
Gene CardMARCKS
Uniprot IDP29966
PfamPF02063
In ASDno
Allosteric Predictionyes (0.570387114)
Ortholog in AnimalsAlpaca_ MARCKS ( ortholog_one2one )
Dog_ MARCKS ( ortholog_one2one )
Macaque_ MARCKS ( ortholog_one2one )
Mouse_ Marcks ( ortholog_one2one )
Pig_ MARCKS ( ortholog_one2one )
Rat_ Marcks ( ortholog_one2one )
Rabbit_ MARCKS ( ortholog_one2one )
OhnologsNA
ParalogsMARCKSL1
TissueNA
Tissue SpecificityNA
Pharmacological Animal Models0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);0.025000(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs45593337  rs3734458 
Subcellular location [CC]Cytoplasm, cytoskeleton {ECO:0000305}. Membrane {ECO:0000305};
Lipid-anchor {ECO:0000305}.
Mouse PG classificationNA
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