| Gene Information | |
|---|---|
| Gene Name | SLC7A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 629 |
| Protein Names | High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homolog) (Ecotropic retrovirus receptor homolog) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter) |
| Target Name | high affinity cationic amino acid transporter 1 |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000139514 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P30825 |
| Gene Card | SLC7A1 |
| Uniprot ID | P30825 |
| Pfam | PF13520; PF13906 |
| In ASD | no |
| Allosteric Prediction | no (-0.006283882) |
| Ortholog in Animals | Alpaca_ SLC7A1 ( ortholog_one2one ) Dog_ SLC7A1 ( ortholog_one2one ) GuineaPig_ SLC7A1 ( ortholog_one2one ) Macaque_ SLC7A1 ( ortholog_one2one ) Mouse_ Slc7a1 ( ortholog_one2one ) Pig_ SLC7A1 ( ortholog_one2one ) Rat_ Slc7a1 ( ortholog_one2one ) Rabbit_ SLC7A1 ( ortholog_one2one ) |
| Ohnologs | SLC7A3, SLC7A2, SLC7A14 |
| Paralogs | SLC7A6, SLC7A10, SLC7A9, SLC7A8, SLC7A11, SLC7A13, SLC7A14, SLC7A7, SLC7A3, SLC7A2, SLC7A4, SLC7A5 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:1718082}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:Q09143}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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