Gene Information
Gene NameHYCC1
OrganismHomo sapiens (Human)
Gene Length521
Protein NamesHyccin (Down-regulated by CTNNB1 protein A)
Target NameNA
Target TypeNA
Gene Age950 ( ENSG00000122591 )
Evolutionary StageEumetazoa
AlphaFoldDBQ9BYI3
Gene CardFAM126A
Uniprot IDQ9BYI3
PfamPF09790
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsHYCC2
ParalogsNA
TissueNA
Tissue SpecificityWidely expressed. Highest levels in heart, brain, placenta, spleen and testis. {ECO:0000269|PubMed:10910037}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.04(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5DSE  (X-ray  2.90A  6BQ1  (EM  3.60A 
DBSNP rs72549407  rs192409840 
Subcellular location [CC]Cytoplasm, cytosol {ECO:0000269|PubMed:10910037, ECO:0000269|PubMed:26571211}. Cell membrane {ECO:0000269|PubMed:16951682, ECO:0000269|PubMed:26571211}. Note=Localizes to the cytosol and is recruited to the plasma membrane following interaction with other components of the phosphatidylinositol 4-kinase (PI4K) complex. {ECO:0000269|PubMed:26571211}.
Mouse PG classificationNA
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