| Gene Information | |
|---|---|
| Gene Name | UBE2E3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 207 |
| Protein Names | Ubiquitin-conjugating enzyme E2 E3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E3) (UbcH9) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (Ubiquitin-protein ligase E3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000170035 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q969T4 |
| Gene Card | UBE2E3 |
| Uniprot ID | Q969T4 |
| Pfam | PF00179 |
| In ASD | no |
| Allosteric Prediction | no (-0.535195682) |
| Ortholog in Animals | Alpaca_ UBE2E3 ( ortholog_one2one ) Dog_ UBE2E3 ( ortholog_one2one ) GuineaPig_ UBE2E3 ( ortholog_one2one ) Macaque_ UBE2E3 ( ortholog_one2one ) Mouse_ Ube2e3 ( ortholog_one2one ) Pig_ UBE2E3 ( ortholog_one2one ) Rat_ Ube2e3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | UBE2Q2, UBE2QL1, UBE2L5, UBE2L3, UBE2E1, UBE2D2, UBE2D3, UBE2E2, UBE2D1, UBE2D4, UBE2Q1, UBE2L6 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed at low levels. Highly expressed in skeletal muscle. {ECO:0000269|PubMed:10343118}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001347(Rat);0.007143(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2368192 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:15545318}. Cytoplasm {ECO:0000269|PubMed:15545318}. Note=Shuttles between the nucleus and cytoplasm in a IPO11-dependent manner. |
| Mouse PG classification | NA |
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