| Gene Information | |
|---|---|
| Gene Name | LY96 |
| Organism | Homo sapiens (Human) |
| Gene Length | 160 |
| Protein Names | Lymphocyte antigen 96 (Ly-96) (ESOP-1) (Protein MD-2) |
| Target Name | lymphocyte antigen 96 |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000154589 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9Y6Y9 |
| Gene Card | LY96 |
| Uniprot ID | Q9Y6Y9 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | yes (0.043300217) |
| Ortholog in Animals | Alpaca_ LY96 ( ortholog_one2one ) Dog_ LY96 ( ortholog_one2one ) GuineaPig_ LY96 ( ortholog_one2one ) Macaque_ LY96 ( ortholog_one2one ) Mouse_ Ly96 ( ortholog_one2one ) Pig_ LY96 ( ortholog_one2one ) Rat_ Ly96 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2E56 (X-ray 2.00A ) 2E59 (X-ray 2.21A ) 2Z65 (X-ray 2.70A ) 3FXI (X-ray 3.10A ) 3ULA (X-ray 3.60A ) 4G8A (X-ray 2.40A ) |
| DBSNP | rs6472812 rs11466004 |
| Subcellular location [CC] | Secreted, extracellular space {ECO:0000269|PubMed:10359581, ECO:0000269|PubMed:11593030, ECO:0000305|PubMed:11274165}. Secreted {ECO:0000269|PubMed:11593030}. Note=Retained in the extracellular space at the cell surface by interaction with TLR4 (PubMed:10359581). {ECO:0000269|PubMed:10359581, ECO:0000269|PubMed:11593030}. |
| Mouse PG classification | NA |
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