| Gene Information | |
|---|---|
| Gene Name | RRP7A |
| Organism | Homo sapiens (Human) |
| Gene Length | 280 |
| Protein Names | Ribosomal RNA-processing protein 7 homolog A (Gastric cancer antigen Zg14) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000189306 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y3A4 |
| Gene Card | RRP7A |
| Uniprot ID | Q9Y3A4 |
| Pfam | PF17799; PF12923 |
| In ASD | no |
| Allosteric Prediction | no (-1.637380601) |
| Ortholog in Animals | Dog_ RRP7 ( ortholog_one2one ) GuineaPig_ RRP7A ( ortholog_one2one ) Macaque_ RRP7A ( ortholog_one2one ) Mouse_ Rrp7a ( ortholog_one2one ) Pig_ RRP7A ( ortholog_one2one ) Rat_ Rrp7a ( ortholog_one2one ) Rabbit_ RRP7A ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in the apical radial glial cells in the developing brain. {ECO:0000269|PubMed:33199730}. |
| Pharmacological Animal Models | 0.137046(Chimpanzee);0.077865(Mouse);0.453614(Rat);0.101135(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7MQ8 (EM 3.60A ) 7MQ9 (EM 3.87A ) 7MQA (EM 2.70A ) |
| DBSNP | rs8139383 rs1812240 rs11553441 rs1356719738 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:33199730}. Cell projection, cilium {ECO:0000269|PubMed:33199730}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:33199730}. |
| Mouse PG classification | NA |
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