| Gene Information | |
|---|---|
| Gene Name | PFKFB1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 471 |
| Protein Names | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 (6PF-2-K/Fru-2,6-P2ase 1) (PFK/FBPase 1) (6PF-2-K/Fru-2,6-P2ase liver isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)] |
| Target Name | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000158571 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P16118 |
| Gene Card | PFKFB1 |
| Uniprot ID | P16118 |
| Pfam | PF01591; PF00300 |
| In ASD | no |
| Allosteric Prediction | yes (1.118203542) |
| Ortholog in Animals | Alpaca_ PFKFB1 ( ortholog_one2one ) Dog_ PFKFB1 ( ortholog_one2one ) GuineaPig_ PFKFB1 ( ortholog_one2one ) Macaque_ PFKFB1 ( ortholog_one2one ) Mouse_ Pfkfb1 ( ortholog_one2one ) Pig_ PFKFB1 ( ortholog_one2one ) Rat_ Pfkfb1 ( ortholog_one2one ) Rabbit_ PFKFB1 ( ortholog_one2one ) |
| Ohnologs | PFKFB4, PFKFB2, PFKFB3 |
| Paralogs | PFKFB4, PFKFB2, PFKFB3 |
| Tissue | adipose.tissue, liver, skeletal.muscle, greater.omentum, subcutaneous.adipose.tissue |
| Tissue Specificity | Liver. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1K6M (X-ray 2.40A ) |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
| click here to return to the previous page | |