| Gene Information | |
|---|---|
| Gene Name | SF3B4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 424 |
| Protein Names | Splicing factor 3B subunit 4 (Pre-mRNA-splicing factor SF3b 49 kDa subunit) (Spliceosome-associated protein 49) (SAP 49) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000143368 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q15427 |
| Gene Card | SF3B4 |
| Uniprot ID | Q15427 |
| Pfam | PF00076 |
| In ASD | no |
| Allosteric Prediction | no (-0.943516652) |
| Ortholog in Animals | Alpaca_ SF3B4 ( ortholog_one2one ) Dog_ SF3B4 ( ortholog_one2one ) GuineaPig_ SF3B4 ( ortholog_one2one ) Macaque_ SF3B4 ( ortholog_one2one ) Mouse_ Sf3b4 ( ortholog_one2one ) Pig_ SF3B4 ( ortholog_one2one ) Rat_ Sf3b4 ( ortholog_one2one ) Rabbit_ SF3B4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RBMS2, PABPC1, PABPC3, RBM24, ELAVL4, ELAVL3, RBMS1, ELAVL2, PUF60, RBM34, RBM45, HNRNPR, SYNCRIP, PABPC1L, PABPC5, RBM14, PABPC1L2A, PABPC1L2B, RBM38, ELAVL1, TARDBP, RBMS3, PABPC4, PABPC4L |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.197287(Rat);0.144422(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1X5T (NMR - ) 5GVQ (NMR - ) 5Z56 (EM 5.10A ) 5Z57 (EM 6.50A ) 5Z58 (EM 4.90A ) 6AH0 (EM 5.70A ) 6AHD (EM 3.80A ) 6QX9 (EM 3.28A ) 6Y53 (EM 7.10A ) 6Y5Q (EM 7.10A ) 7ABG (EM 7.80A ) 7ABH (EM 4.50A ) 7ABI (EM 8.00A ) 7DVQ (EM 2.89A ) 7EVO (EM 2.50A ) 7ONB (EM 3.10A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:27720643, ECO:0000269|PubMed:28541300}. |
| Mouse PG classification | NA |
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