| Gene Information | |
|---|---|
| Gene Name | DCXR |
| Organism | Homo sapiens (Human) |
| Gene Length | 244 |
| Protein Names | L-xylulose reductase (XR) (EC 1.1.1.10) (Carbonyl reductase II) (Dicarbonyl/L-xylulose reductase) (Kidney dicarbonyl reductase) (kiDCR) (Short chain dehydrogenase/reductase family 20C member 1) (Sperm surface protein P34H) |
| Target Name | l-xylulose reductase |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000169738 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q7Z4W1 |
| Gene Card | DCXR |
| Uniprot ID | Q7Z4W1 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.395408701) |
| Ortholog in Animals | Alpaca_ DCXR ( ortholog_one2one ) Dog_ DCXR ( ortholog_one2one ) GuineaPig_ Dcxr ( ortholog_one2one ) Macaque_ DCXR ( ortholog_one2one ) Mouse_ Dcxr ( ortholog_one2one ) Pig_ DCXR ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis. {ECO:0000269|PubMed:10385429, ECO:0000269|PubMed:11882650}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 1PR9 (X-ray 1.96A ) 1WNT (X-ray 2.30A ) 3D3W (X-ray 1.87A ) |
| DBSNP | NA |
| Subcellular location [CC] | Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Probably recruited to membranes via an interaction with phosphatidylinositol. {ECO:0000250}. |
| Mouse PG classification | NA |
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