| Gene Information | |
|---|---|
| Gene Name | ZHX2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 837 |
| Protein Names | Zinc fingers and homeoboxes protein 2 (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP) (Zinc finger and homeodomain protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 8 ( ENSG00000178764 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9Y6X8 |
| Gene Card | ZHX2 |
| Uniprot ID | Q9Y6X8 |
| Pfam | PF00046; PF18387 |
| In ASD | no |
| Allosteric Prediction | yes (0.104989503) |
| Ortholog in Animals | Alpaca_ ZHX2 ( ortholog_one2one ) Dog_ ZHX2 ( ortholog_one2one ) GuineaPig_ ZHX2 ( ortholog_one2one ) Macaque_ ZHX2 ( ortholog_one2one ) Mouse_ Zhx2 ( ortholog_one2one ) Pig_ ZHX2 ( ortholog_one2one ) Rat_ Zhx2 ( ortholog_one2one ) Rabbit_ ZHX2 ( ortholog_one2one ) |
| Ohnologs | ZHX3 |
| Paralogs | ZHX1, ZHX3, HOMEZ |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. Expressed in podocytes. {ECO:0000269|PubMed:12741956, ECO:0000269|PubMed:17056598}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 2DMP (NMR - ) 3NAU (X-ray 2.70A ) |
| DBSNP | rs9649951 rs35319449 rs3802264 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:12741956, ECO:0000269|PubMed:17056598}. Note=Colocalizes with EFNB1 intracellular domain in the nucleus. {ECO:0000250|UniProtKB:Q8C0C0}. |
| Mouse PG classification | NA |
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