| Gene Information | |
|---|---|
| Gene Name | GABRP |
| Organism | Homo sapiens (Human) |
| Gene Length | 440 |
| Protein Names | Gamma-aminobutyric acid receptor subunit pi (GABA(A) receptor subunit pi) |
| Target Name | gaba(a) receptor |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000094755 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O00591 |
| Gene Card | GABRP |
| Uniprot ID | O00591 |
| Pfam | PF02931; PF02932 |
| In ASD | no |
| Allosteric Prediction | yes (0.791758645) |
| Ortholog in Animals | Alpaca_ GABRP ( ortholog_one2one ) Dog_ GABRP ( ortholog_one2one ) GuineaPig_ GABRP ( ortholog_one2one ) Macaque_ GABRP ( ortholog_one2one ) Mouse_ Gabrp ( ortholog_one2one ) Pig_ GABRP ( ortholog_one2one ) Rat_ Gabrp ( ortholog_one2one ) Rabbit_ GABRP ( ortholog_one2one ) |
| Ohnologs | GABRA3, GLRA2, GABRR2, GABRR1, GLRA4, GLRB, GLRA3 |
| Paralogs | CHRNB1, GABRR2, CHRNA6, CHRNB4, CHRNA4, GABRQ, HTR3E, CHRNA1, CHRNA3, GABRA5, GLRA2, HTR3B, GLRA1, GABRG3, GABRA2, GABRB3, HTR3C, HTR3D, GABRG1, CHRNA7, CHRFAM7A, GABRD, GABRR1, CHRNA5, GABRA6, GABRA4, GLRA3, GABRE, CHRNE, GABRG2, CHRND, CHRNA2, CHRNA10, CHRNA9, GABRA3, HTR3A, ZACN, CHRNB3, CHRNB2, CHRNG, GABRR3, GABRB2, GABRB1, GABRA1, GLRB |
| Tissue | endometrium, esophagus, tonsil, breast, cervix, uterus, vagina, esophagus.mucosa, lower.leg.skin, minor.salivary.gland, suprapubic.skin |
| Tissue Specificity | Most abundant in the uterus, also expressed in lung, thymus and prostate. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs1063310 rs1290926314 |
| Subcellular location [CC] | Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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