| Gene Information | |
|---|---|
| Gene Name | SLC9A6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 669 |
| Protein Names | Sodium/hydrogen exchanger 6 (Na(+)/H(+) exchanger 6) (NHE-6) (Solute carrier family 9 member 6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000198689 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q92581 |
| Gene Card | SLC9A6 |
| Uniprot ID | Q92581 |
| Pfam | PF00999 |
| In ASD | no |
| Allosteric Prediction | no (-1.031314078) |
| Ortholog in Animals | Alpaca_ SLC9A6 ( ortholog_one2one ) Dog_ SLC9A6 ( ortholog_one2one ) GuineaPig_ SLC9A6 ( ortholog_one2one ) Macaque_ SLC9A6 ( ortholog_one2one ) Mouse_ Slc9a6 ( ortholog_one2one ) Pig_ SLC9A6 ( ortholog_one2one ) Rat_ Slc9a6 ( ortholog_one2one ) Rabbit_ SLC9A6 ( ortholog_one2one ) |
| Ohnologs | SLC9A9 |
| Paralogs | SLC9A7, SLC9C1, SLC9A4, SLC9A1, SLC9A9, SLC9A5, SLC9A3, SLC9A2, SLC9A8, SLC9C2 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous; but is most abundant in mitochondrion-rich tissues such as brain, skeletal muscle and heart. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endosome membrane {ECO:0000269|PubMed:11940519}; Multi-pass membrane protein {ECO:0000269|PubMed:11940519}. Note=Is present in the recycling compartments including early and recycling endosomes, and only appears transiently on the plasma membrane.; [Isoform 2]: Recycling endosome membrane {ECO:0000269|PubMed:30296617}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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