| Gene Information | |
|---|---|
| Gene Name | RAG1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1043 |
| Protein Names | V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74) [Includes: Endonuclease RAG1 (EC 3.1.-.-); E3 ubiquitin-protein ligase RAG1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RAG1)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000166349 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P15918 |
| Gene Card | RAG1 |
| Uniprot ID | P15918 |
| Pfam | PF12940; PF12560; PF10426 |
| In ASD | no |
| Allosteric Prediction | yes (0.088608607) |
| Ortholog in Animals | Alpaca_ RAG1 ( ortholog_one2one ) Dog_ RAG1 ( ortholog_one2one ) GuineaPig_ RAG1 ( ortholog_one2one ) Macaque_ RAG1 ( ortholog_one2one ) Mouse_ Rag1 ( ortholog_one2one ) Pig_ RAG1 ( ortholog_one2one ) Rat_ Rag1 ( ortholog_one2one ) Rabbit_ RAG1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Maturing lymphoid cells. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1801203 rs4151027 rs199474683 rs4151029 rs3740955 rs4151030 rs121918568 rs121918571 rs773272902 rs104894289 rs104894291 rs104894291 rs199474682 rs199474684 rs104894292 rs199474679 rs141524540 rs199474685 rs4151031 rs199474677 rs199474678 rs199474686 rs104894298 rs193922461 rs4151032 rs199474681 rs104894285 rs104894284 rs1850821995 rs199474688 rs199474680 rs199474689 rs199474676 rs28933392 rs104894286 rs199474687 rs121918569 rs2227973 rs104894287 rs199474690 rs4151033 rs199474691 rs4151034 rs104894290 rs150739647 rs121918570 rs104894288 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00820}. |
| Mouse PG classification | NA |
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