| Gene Information | |
|---|---|
| Gene Name | HYAL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 473 |
| Protein Names | Hyaluronidase-2 (Hyal-2) (EC 3.2.1.35) (Hyaluronoglucosaminidase-2) (Lung carcinoma protein 2) (LuCa-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000068001 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q12891 |
| Gene Card | HYAL2 |
| Uniprot ID | Q12891 |
| Pfam | PF01630 |
| In ASD | no |
| Allosteric Prediction | yes (0.225306797) |
| Ortholog in Animals | Alpaca_ HYAL2 ( ortholog_one2one ) GuineaPig_ HYAL2 ( ortholog_one2one ) Macaque_ HYAL2 ( ortholog_one2one ) Mouse_ Hyal2 ( ortholog_one2one ) Pig_ HYAL2 ( ortholog_one2one ) Rat_ Hyal2 ( ortholog_one2one ) Rabbit_ HYAL2 ( ortholog_one2one ) |
| Ohnologs | HYAL4, SPAM1 |
| Paralogs | HYAL4, HYAL3, HYAL1, SPAM1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. No expression detected in adult brain. {ECO:0000269|PubMed:9712871}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs709210 rs35455589 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:11296287}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:11296287}. |
| Mouse PG classification | NA |
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