| Gene Information | |
|---|---|
| Gene Name | OPRD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 372 |
| Protein Names | Delta-type opioid receptor (D-OR-1) (DOR-1) |
| Target Name | opioid receptor delta |
| Target Type | Successful target |
| Gene Age | 645 ( ENSG00000116329 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P41143 |
| Gene Card | OPRD1 |
| Uniprot ID | P41143 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | yes (1.249251467) |
| Ortholog in Animals | Alpaca_ OPRD1 ( ortholog_one2one ) Dog_ OPRD1 ( ortholog_one2one ) GuineaPig_ OPRD1 ( ortholog_one2one ) Mouse_ Oprd1 ( ortholog_one2one ) Pig_ OPRD1 ( ortholog_one2one ) Rat_ Oprd1 ( ortholog_one2one ) Rabbit_ OPRD1 ( ortholog_one2one ) |
| Ohnologs | OPRK1, OPRM1, OPRL1, NPBWR2, MCHR1, SSTR4 |
| Paralogs | SSTR5, SSTR4, NPBWR1, OPRL1, GPR149, OPRM1, OPRK1, PTGDR2, SSTR3, CMKLR2, SSTR1, LTB4R, LTB4R2, KISS1R, UTS2R, NPBWR2, SSTR2 |
| Tissue | NA |
| Tissue Specificity | Detected in oocytes (at protein level). Detected in brain cortex, hypothalamus, hippocampus and olfactory bulb. Detected in oocytes. {ECO:0000269|PubMed:22417668, ECO:0000269|PubMed:7808419}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 4N6H (X-ray 1.80A ) 4RWA (X-ray 3.28A ) 4RWD (X-ray 2.70A ) 6PT2 (X-ray 2.80A ) 6PT3 (X-ray 3.30A ) |
| DBSNP | rs1042114 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:22184124, ECO:0000269|PubMed:7808419, ECO:0000269|PubMed:8201839}; Multi-pass membrane protein {ECO:0000269|PubMed:22184124, ECO:0000269|PubMed:7808419, ECO:0000269|PubMed:8201839}. |
| Mouse PG classification | NA |
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