| Gene Information | |
|---|---|
| Gene Name | OPN2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 348 |
| Protein Names | Rhodopsin (Opsin-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P08100 |
| Gene Card | RHO |
| Uniprot ID | P08100 |
| Pfam | PF00001; PF10413 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Rod shaped photoreceptor cells which mediate vision in dim light. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003990(Rat);0.1(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4ZWJ (X-ray 3.30A ) 5DGY (X-ray 7.70A ) 5W0P (X-ray 3.01A ) 6CMO (EM 4.50A ) |
| DBSNP | rs104893786 rs104893769 rs104893768 rs774336493 rs104893770 rs149079952 rs104893792 rs28933395 rs28933394 rs104893771 rs104893772 rs104893790 rs104893796 rs144317206 rs104893773 rs104893773 rs1415160298 rs104893787 rs104893788 rs1553781140 rs104893774 rs104893775 rs104893791 rs104893793 rs104893793 rs2084776162 rs104893794 rs104893776 rs775557680 rs104893780 rs1424131846 rs527236100 rs104893777 rs104893779 rs104893779 rs104893782 rs567288669 rs28933993 rs766161322 rs104893781 rs104893789 rs29001653 rs142285818 rs183318466 rs104893795 rs104893795 rs29001566 rs29001566 rs29001566 rs29001637 |
| Subcellular location [CC] | Membrane {ECO:0000269|PubMed:12566452, ECO:0000269|PubMed:19934218, ECO:0000269|PubMed:25664179, ECO:0000269|PubMed:26200343, ECO:0000269|PubMed:28753425}; Multi-pass membrane protein {ECO:0000269|PubMed:19934218, ECO:0000269|PubMed:26200343, ECO:0000269|PubMed:28753425}. Cell projection, cilium, photoreceptor outer segment {ECO:0000269|PubMed:25664179}. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia. {ECO:0000269|PubMed:25664179}. |
| Mouse PG classification | NA |
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