Gene Information
Gene NameOPLAH
OrganismHomo sapiens (Human)
Gene Length1288
Protein Names5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (5-OPase) (Pyroglutamase)
Target Name5-oxoprolinase
Target TypeNA
Gene Age680 ( ENSG00000178814 )
Evolutionary StageCellular_organisms
AlphaFoldDBO14841
Gene CardOPLAH
Uniprot IDO14841
PfamPF05378; PF01968; PF02538
In ASDno
Allosteric Predictionno (-0.304878569)
Ortholog in AnimalsAlpaca_ OPLAH ( ortholog_one2one )
Dog_ OPLAH ( ortholog_one2one )
GuineaPig_ OPLAH ( ortholog_one2one )
Macaque_ OPLAH ( ortholog_one2one )
Mouse_ Oplah ( ortholog_one2one )
Pig_ OPLAH ( ortholog_one2one )
Rat_ Oplah ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs3935209 
Subcellular location [CC]NA
Mouse PG classificationLPG
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