| Gene Information | |
|---|---|
| Gene Name | OPHN1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 802 |
| Protein Names | Oligophrenin-1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000079482 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O60890 |
| Gene Card | OPHN1 |
| Uniprot ID | O60890 |
| Pfam | PF00169; PF00620 |
| In ASD | no |
| Allosteric Prediction | no (-0.325092547) |
| Ortholog in Animals | Alpaca_ OPHN1 ( ortholog_one2one ) Dog_ OPHN1 ( ortholog_one2one ) GuineaPig_ OPHN1 ( ortholog_one2one ) Macaque_ OPHN1 ( ortholog_one2one ) Mouse_ Ophn1 ( ortholog_one2one ) Pig_ OPHN1 ( ortholog_one2one ) Rat_ Ophn1 ( ortholog_one2one ) Rabbit_ OPHN1 ( ortholog_one2one ) |
| Ohnologs | ARHGAP10, ARHGAP26, ARHGAP42 |
| Paralogs | ARHGAP10, ARHGAP42, ARHGAP26 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs41303733 rs148262378 rs138108344 rs36095561 |
| Subcellular location [CC] | Postsynapse {ECO:0000250|UniProtKB:P0CAX5}. Presynapse {ECO:0000250|UniProtKB:P0CAX5}. Cell projection, axon {ECO:0000250|UniProtKB:P0CAX5}. Cell projection, dendritic spine {ECO:0000250|UniProtKB:P0CAX5}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q99J31}. Cytoplasm {ECO:0000250|UniProtKB:Q99J31}. |
| Mouse PG classification | LPG |
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