| Gene Information | |
|---|---|
| Gene Name | CLEC12B |
| Organism | Homo sapiens (Human) |
| Gene Length | 276 |
| Protein Names | C-type lectin domain family 12 member B (Macrophage antigen H) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000256660 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q2HXU8 |
| Gene Card | CLEC12B |
| Uniprot ID | Q2HXU8 |
| Pfam | PF00059; PF08391 |
| In ASD | no |
| Allosteric Prediction | no (-1.261769667) |
| Ortholog in Animals | Alpaca_ CLEC12B ( ortholog_one2one ) Dog_ CLEC12B ( ortholog_one2one ) Macaque_ CLEC12B ( ortholog_one2one ) Mouse_ Clec12b ( ortholog_one2one ) Pig_ CLEC12B ( ortholog_one2one ) Rat_ Clec12b ( ortholog_one2one ) Rabbit_ CLEC12B ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CD69, CLEC12A, KLRC3, KLRC2, OLR1, KLRG2, CLEC2A, KLRF1, CLEC1A, KLRF2, KLRD1, CLEC2B, KLRC1, CLEC2L, KLRG1, CLEC9A, CLEC1B, KLRC4, KLRK1, CLEC5A, CLEC2D, CLEC7A, KLRB1 |
| Tissue | testis |
| Tissue Specificity | Detected in colon, heart, kidney, liver, lung, mammary gland, ovary, spleen and testis (PubMed:17562706). Expressed in melanocytes (at protein level) (PubMed:34310951). {ECO:0000269|PubMed:17562706, ECO:0000269|PubMed:34310951}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1359082 rs637790 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:17562706}; Single-pass type II membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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