| Gene Information | |
|---|---|
| Gene Name | OLFML2A |
| Organism | Homo sapiens (Human) |
| Gene Length | 652 |
| Protein Names | Olfactomedin-like protein 2A (Photomedin-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000185585 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q68BL7 |
| Gene Card | OLFML2A |
| Uniprot ID | Q68BL7 |
| Pfam | PF02191 |
| In ASD | no |
| Allosteric Prediction | no (-1.466751072) |
| Ortholog in Animals | Alpaca_ OLFML2A ( ortholog_one2one ) Dog_ OLFML2A ( ortholog_one2one ) GuineaPig_ OLFML2A ( ortholog_one2one ) Macaque_ OLFML2A ( ortholog_one2one ) Mouse_ Olfml2a ( ortholog_one2one ) Pig_ OLFML2A ( ortholog_one2one ) Rat_ Olfml2a ( ortholog_one2one ) Rabbit_ OLFML2A ( ortholog_one2one ) |
| Ohnologs | MYOC, OLFM3, OLFML2B |
| Paralogs | OLFML1, OLFM2, OLFM3, OLFM1, OLFML2B, GLDN, MYOC, OLFM4, OLFML3 |
| Tissue | NA |
| Tissue Specificity | In the kidney expressed only by podocytes, wherein they localize to major processes. {ECO:0000269|PubMed:22913984}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7874348 rs16927649 |
| Subcellular location [CC] | Secreted {ECO:0000250|UniProtKB:Q8BHP7}. Note=Localizes to the podocyte major processes. Colocalized with the major process protein VIM throughout podocyte development. {ECO:0000269|PubMed:22913984}. |
| Mouse PG classification | NA |
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