| Gene Information | |
|---|---|
| Gene Name | FZD9 |
| Organism | Homo sapiens (Human) |
| Gene Length | 591 |
| Protein Names | Frizzled-9 (Fz-9) (hFz9) (FzE6) (CD antigen CD349) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000188763 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O00144 |
| Gene Card | FZD9 |
| Uniprot ID | O00144 |
| Pfam | PF01534; PF01392 |
| In ASD | no |
| Allosteric Prediction | no (-0.608260586) |
| Ortholog in Animals | Alpaca_ FZD9 ( ortholog_one2one ) Dog_ FZD9 ( ortholog_one2one ) GuineaPig_ FZD9 ( ortholog_one2one ) Macaque_ FZD9 ( ortholog_one2one ) Mouse_ Fzd9 ( ortholog_one2one ) Pig_ FZD9 ( ortholog_one2one ) Rat_ Fzd9 ( ortholog_one2one ) Rabbit_ FZD9 ( ortholog_one2one ) |
| Ohnologs | FZD10, FZD4, FZD8, FZD5 |
| Paralogs | SFRP5, SFRP1, FZD5, FZD2, FZD10, SFRP4, FZD7, FRZB, FZD6, FZD8, SMO, FZD1, SFRP2, FZD4, FZD3 |
| Tissue | NA |
| Tissue Specificity | Expressed predominantly in adult and fetal brain, testis, eye, skeletal muscle and kidney. Moderately expressed in pancreas, thyroid, adrenal cortex, small intestine and stomach. Detected in fetal liver and kidney. Expressed in neural progenitor cells (PubMed:27509850). {ECO:0000269|PubMed:27509850}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:Q9R216}; Multi-pass membrane protein {ECO:0000255}. Note=Relocalizes DVL1 to the cell membrane leading to phosphorylation of DVL1 and AXIN1 relocalization to the cell membrane. {ECO:0000250|UniProtKB:Q8K4C8}. |
| Mouse PG classification | NA |
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