| Gene Information | |
|---|---|
| Gene Name | TRIM46 |
| Organism | Homo sapiens (Human) |
| Gene Length | 759 |
| Protein Names | Tripartite motif-containing protein 46 (Gene Y protein) (GeneY) (Tripartite, fibronectin type-III and C-terminal SPRY motif protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000163462 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q7Z4K8 |
| Gene Card | TRIM46 |
| Uniprot ID | Q7Z4K8 |
| Pfam | PF18568; PF00643 |
| In ASD | no |
| Allosteric Prediction | no (-0.364000988) |
| Ortholog in Animals | Alpaca_ TRIM46 ( ortholog_one2one ) Dog_ TRIM46 ( ortholog_one2one ) GuineaPig_ TRIM46 ( ortholog_one2one ) Macaque_ TRIM46 ( ortholog_one2one ) Mouse_ Trim46 ( ortholog_one2one ) Pig_ TRIM46 ( ortholog_one2one ) Rat_ Trim46 ( ortholog_one2one ) Rabbit_ TRIM46 ( ortholog_one2one ) |
| Ohnologs | FSD1, FSD1L, TRIM55, TRIM36, FSD2 |
| Paralogs | TRIM42, TRIM13, TRIM31, TRIM49B, TRIM49C, TRIM49, TRIM33, TRIM69, TRIM71, TRIM77, TRIM28, TRIM3, TRIM58, TRIM38, TRIM5, TRIM37, MID1, TRIM7, TRIM36, TRIM44, TRIML2, TRIM2, TRIM63, TRIM73, TRIM74, TRIM65, TRIML1, MID2, TRIM32, TRIM14, TRIM34, TRIM54, TRIM55, TRIM52, TRIM41, TRIM11, PML, TRIM43, TRIM43B, TRIM21, TRIM6, TRIM27, TRIM40, TRIM51G, TRIM51, TRIM9, TRIM67, TRIM25, TRIM49D1, TRIM48, TRIM49D2, TRIM68, TRIM17, TRIM24, TRIM64C, TRIM64, TRIM64B, TRIM60, TRIM61, TRIM4, TRIM10, BSPRY, TRIM56, TRIM29, TRIM8, MEFV, TRIM15, TRIM22, TRIM35, TRIM16, TRIM47, TRIM45, TRIM72, TRIM62, TRIM50, TRIM75, TRIM66, RNF39, TRIM26, TRIM39 |
| Tissue | cerebellar.hemisphere, cerebellum |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell projection, axon {ECO:0000250|UniProtKB:Q7TNM2}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q7TNM2}. Note=Microtubule-associated. Localizes to the proximal part of the axon. {ECO:0000250|UniProtKB:Q7TNM2}. |
| Mouse PG classification | NA |
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