| Gene Information | |
|---|---|
| Gene Name | OLAH |
| Organism | Homo sapiens (Human) |
| Gene Length | 265 |
| Protein Names | S-acyl fatty acid synthase thioesterase, medium chain (EC 3.1.2.14) (Augmented in rheumatoid arthritis 1) (AURA1) (Oleoyl-ACP hydrolase) (Thioesterase 2) (TE2) (Thioesterase II) (Thioesterase domain-containing protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000152463 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9NV23 |
| Gene Card | OLAH |
| Uniprot ID | Q9NV23 |
| Pfam | PF00975 |
| In ASD | no |
| Allosteric Prediction | no (-1.196400554) |
| Ortholog in Animals | Alpaca_ OLAH ( ortholog_one2one ) GuineaPig_ OLAH ( ortholog_one2one ) Macaque_ OLAH ( ortholog_one2one ) Mouse_ Olah ( ortholog_one2one ) Rat_ Olah ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | testis, lung, spleen |
| Tissue Specificity | Detected both in lactating and non-lactating breast epithelium (at protein level) (PubMed:6589427). Isoform 2 is up-regulated in bone marrow-derived mononuclear cells of rheumatoid arthritis patients (PubMed:17082220). {ECO:0000269|PubMed:17082220, ECO:0000269|PubMed:6589427}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 4XJV (X-ray 2.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000250|UniProtKB:P08635}. |
| Mouse PG classification | NA |
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