| Gene Information | |
|---|---|
| Gene Name | OLA1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 396 |
| Protein Names | Obg-like ATPase 1 (DNA damage-regulated overexpressed in cancer 45) (DOC45) (GTP-binding protein 9) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000138430 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9NTK5 |
| Gene Card | OLA1 |
| Uniprot ID | Q9NTK5 |
| Pfam | PF01926; PF06071 |
| In ASD | no |
| Allosteric Prediction | yes (0.341048264) |
| Ortholog in Animals | Alpaca_ OLA1 ( ortholog_one2one ) Dog_ OLA1 ( ortholog_one2one ) GuineaPig_ OLA1 ( ortholog_one2one ) Macaque_ OLA1 ( ortholog_one2one ) Mouse_ Ola1 ( ortholog_one2one ) Pig_ OLA1 ( ortholog_one2one ) Rat_ Ola1 ( ortholog_one2one ) Rabbit_ OLA1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues tested but its expression is more abundant in testis, liver, lung, and brain. Overexpressed in several malignancies, including cancers of the colon, rectum, ovary, lung, stomach, and uterus. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.025(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2OHF (X-ray 2.70A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03167, ECO:0000269|PubMed:20053727}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03167, ECO:0000269|PubMed:20053727}. Nucleus, nucleolus {ECO:0000255|HAMAP-Rule:MF_03167, ECO:0000269|PubMed:20053727}. Note=Predominantly cytoplasmic, shuttles between the nucleus and the cytoplasm. {ECO:0000255|HAMAP-Rule:MF_03167}. |
| Mouse PG classification | NA |
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