| Gene Information | |
|---|---|
| Gene Name | AIF1L |
| Organism | Homo sapiens (Human) |
| Gene Length | 150 |
| Protein Names | Allograft inflammatory factor 1-like (Ionized calcium-binding adapter molecule 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000126878 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9BQI0 |
| Gene Card | AIF1L |
| Uniprot ID | Q9BQI0 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.333464477) |
| Ortholog in Animals | Alpaca_ AIF1L ( ortholog_one2one ) Dog_ AIF1L ( ortholog_one2one ) GuineaPig_ AIF1L ( ortholog_one2one ) Macaque_ AIF1L ( ortholog_one2one ) Mouse_ Aif1l ( ortholog_one2one ) Pig_ AIF1L ( ortholog_one2one ) Rat_ Aif1l ( ortholog_one2one ) |
| Ohnologs | AIF1 |
| Paralogs | AIF1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2JJZ (X-ray 2.15A ) 2VTG (X-ray 2.45A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:18699778}. Cell projection, ruffle membrane {ECO:0000269|PubMed:18699778}; Peripheral membrane protein {ECO:0000269|PubMed:18699778}; Cytoplasmic side {ECO:0000269|PubMed:18699778}. Note=Colocalizes with F-actin. Partially relocates to membrane ruffles in response to invading bacteria. |
| Mouse PG classification | NA |
| click here to return to the previous page | |