| Gene Information | |
|---|---|
| Gene Name | OK/SW-cl.12 |
| Organism | Homo sapiens (Human) |
| Gene Length | 335 |
| Protein Names | Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) (Peptidyl-cysteine S-nitrosylase GAPDH) (EC 2.6.99.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P04406 |
| Gene Card | GAPDH |
| Uniprot ID | P04406 |
| Pfam | PF02800; PF00044 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.027778(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1U8F (X-ray 1.75A ) 1ZNQ (X-ray 2.50A ) 3GPD (X-ray 3.50A ) 4WNC (X-ray 1.99A ) 4WNI (X-ray 2.30A ) 6ADE (X-ray 3.15A ) 6IQ6 (X-ray 2.29A ) 6M61 (X-ray 1.82A ) 6YND (X-ray 1.52A ) 6YNE (X-ray 1.85A ) 6YNF (X-ray 2.39A ) 6YNH (X-ray 2.62A ) |
| DBSNP | rs45541435 rs1062429 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:12829261}. Nucleus {ECO:0000250|UniProtKB:P04797}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:12829261}. Membrane {ECO:0000269|PubMed:12829261}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P04797}. Note=Translocates to the nucleus following S-nitrosylation and interaction with SIAH1, which contains a nuclear localization signal (By similarity). Postnuclear and Perinuclear regions (PubMed:12829261). {ECO:0000250|UniProtKB:P04797, ECO:0000269|PubMed:12829261}. |
| Mouse PG classification | NA |
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