| Gene Information | |
|---|---|
| Gene Name | OIP4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 509 |
| Protein Names | Melanoma antigen preferentially expressed in tumors (Opa-interacting protein 4) (OIP-4) (Preferentially expressed antigen of melanoma) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P78395 |
| Gene Card | PRAME |
| Uniprot ID | P78395 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in testis. Detected in samples of kidney, brain and skin. {ECO:0000269|PubMed:9047241}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1129172 rs41277507 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:21822215, ECO:0000269|PubMed:23460923, ECO:0000305|PubMed:16620968}. Chromosome {ECO:0000269|PubMed:21822215}. Cytoplasm {ECO:0000269|PubMed:23460923}. Golgi apparatus {ECO:0000269|PubMed:23460923}. Cell membrane {ECO:0000269|PubMed:16620968}. Note=Associates with chromatin; specifically enriched at transcriptionally active promoters that are also bound by nuclear transcription factor Y (composed of NFYA, NFYB and NFYC) and at enhancers (PubMed:21822215). Recruited to the Golgi apparatus in response to interferon gamma (IFNG) treatment (PubMed:23460923). {ECO:0000269|PubMed:21822215, ECO:0000269|PubMed:23460923}. |
| Mouse PG classification | NA |
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