| Gene Information | |
|---|---|
| Gene Name | SGRF |
| Organism | Homo sapiens (Human) |
| Gene Length | 189 |
| Protein Names | Interleukin-23 subunit alpha (IL-23 subunit alpha) (IL-23-A) (Interleukin-23 subunit p19) (IL-23p19) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9NPF7 |
| Gene Card | IL23A |
| Uniprot ID | Q9NPF7 |
| Pfam | PF16649 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Secreted by activated dendritic and phagocytic cells and keratinocytes. Also expressed by dermal Langerhans cells (at protein level). {ECO:0000269|PubMed:11114383, ECO:0000269|PubMed:16424222}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002657(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3D85 (X-ray 1.90A ) 3D87 (X-ray 2.90A ) 3DUH (X-ray 2.30A ) 3QWR (X-ray 3.25A ) 4GRW (X-ray 2.55A ) 5MJ3 (X-ray 1.74A ) 5MJ4 (X-ray 3.40A ) 5MXA (X-ray 2.50A ) 5MZV (X-ray 2.80A ) 5NJD (X-ray 3.90A ) 6UIB (X-ray 2.74A ) 6WDQ (X-ray 3.40A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:11114383}. Note=Secreted upon association with IL12B. |
| Mouse PG classification | NA |
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