| Gene Information | |
|---|---|
| Gene Name | OGFR |
| Organism | Homo sapiens (Human) |
| Gene Length | 677 |
| Protein Names | Opioid growth factor receptor (OGFr) (Protein 7-60) (Zeta-type opioid receptor) |
| Target Name | opioid receptor zeta |
| Target Type | Clinical trial target |
| Gene Age | 454 ( ENSG00000060491 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NZT2 |
| Gene Card | OGFR |
| Uniprot ID | Q9NZT2 |
| Pfam | PF04680; PF04664 |
| In ASD | no |
| Allosteric Prediction | no (-0.670969549) |
| Ortholog in Animals | Alpaca_ OGFR ( ortholog_one2one ) GuineaPig_ OGFR ( ortholog_one2one ) Macaque_ OGFR ( ortholog_one2one ) Mouse_ Ogfr ( ortholog_one2one ) Rat_ Ogfr ( ortholog_one2one ) |
| Ohnologs | OGFRL1 |
| Paralogs | OGFRL1 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in the heart and liver, moderately in skeletal muscle and kidney and to a lesser extent in brain and pancreas. Expressed in fetal tissues including liver and kidney. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6122313 rs6122315 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=The OGF/OGFR complex is probably translocated to the nucleus. |
| Mouse PG classification | NA |
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