| Gene Information | |
|---|---|
| Gene Name | SLC7A3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 619 |
| Protein Names | Cationic amino acid transporter 3 (CAT-3) (CAT3) (Cationic amino acid transporter y+) (Solute carrier family 7 member 3) |
| Target Name | cationic amino acid transporter 3 |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000165349 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q8WY07 |
| Gene Card | SLC7A3 |
| Uniprot ID | Q8WY07 |
| Pfam | PF13520; PF13906 |
| In ASD | no |
| Allosteric Prediction | no (-0.495253344) |
| Ortholog in Animals | Alpaca_ SLC7A3 ( ortholog_one2one ) Dog_ SNX12 ( ortholog_one2many ) GuineaPig_ SLC7A3 ( ortholog_one2one ) Macaque_ SLC7A3 ( ortholog_one2one ) Mouse_ Slc7a3 ( ortholog_one2one ) Pig_ SLC7A3 ( ortholog_one2one ) Rat_ Slc7a3 ( ortholog_one2one ) Rabbit_ SLC7A3 ( ortholog_one2one ) |
| Ohnologs | SLC7A2, SLC7A1 |
| Paralogs | SLC7A6, SLC7A10, SLC7A9, SLC7A8, SLC7A11, SLC7A13, SLC7A14, SLC7A7, SLC7A2, SLC7A4, SLC7A1, SLC7A5 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in thymus, uterus and testis (PubMed:11591158). Detected at lower levels in brain, mammary gland, prostate, salivary gland and fetal spleen (PubMed:11591158). In brain, highest expression in thalamus, hippocampus and amygdala (PubMed:11591158). {ECO:0000269|PubMed:11591158}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6525447 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
| click here to return to the previous page | |