| Gene Information | |
|---|---|
| Gene Name | STRADB |
| Organism | Homo sapiens (Human) |
| Gene Length | 418 |
| Protein Names | STE20-related kinase adapter protein beta (STRAD beta) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein) (CALS-21) (ILP-interacting protein) (Pseudokinase ALS2CR2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000082146 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9C0K7 |
| Gene Card | STRADB |
| Uniprot ID | Q9C0K7 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | yes (0.393800171) |
| Ortholog in Animals | Alpaca_ STRADB ( ortholog_one2one ) Dog_ STRADB ( ortholog_one2one ) GuineaPig_ STRADB ( ortholog_one2one ) Macaque_ STRADB ( ortholog_one2one ) Mouse_ Stradb ( ortholog_one2one ) Pig_ STRADB ( ortholog_one2one ) Rat_ Stradb ( ortholog_one2one ) Rabbit_ STRADB ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PAK5, PAK6, PAK4, SBK2, STK39, MAP4K1, PAK2, PAK1, PAK3, MINK1, TNIK, MAP4K5, SLK, MAP3K14, MAP3K19, STK4, MAP3K1, TAOK2, MAP4K3, NRK, STRADA, MAP2K3, STK10, MAP2K6, STK26, TAOK3, TAOK1, MAP3K8, MAP4K2, OXSR1, STK3, NEK4, STK25, STK24, MAP4K4 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in heart, skeletal muscle, testis, liver and colon. {ECO:0000269|PubMed:11161814, ECO:0000269|PubMed:12048196}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs35636836 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:14517248}. Cytoplasm {ECO:0000269|PubMed:14517248}. |
| Mouse PG classification | NA |
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