| Gene Information | |
|---|---|
| Gene Name | LAMB2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1609 |
| Protein Names | Laminin subunit gamma-1 (Laminin B2 chain) (Laminin-1 subunit gamma) (Laminin-10 subunit gamma) (Laminin-11 subunit gamma) (Laminin-2 subunit gamma) (Laminin-3 subunit gamma) (Laminin-4 subunit gamma) (Laminin-6 subunit gamma) (Laminin-7 subunit gamma) (Laminin-8 subunit gamma) (Laminin-9 subunit gamma) (S-laminin subunit gamma) (S-LAM gamma) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000172037 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P11047 |
| Gene Card | LAMC1 |
| Uniprot ID | P11047 |
| Pfam | PF00052; PF00053; PF00055 |
| In ASD | no |
| Allosteric Prediction | no (-0.785448925) |
| Ortholog in Animals | Alpaca_ LAMB2 ( ortholog_one2one ) Dog_ LAMB2 ( ortholog_one2one ) GuineaPig_ LAMB2 ( ortholog_one2one ) Macaque_ LAMB2 ( ortholog_one2one ) Mouse_ Lamb2 ( ortholog_one2one ) Pig_ LAMB2 ( ortholog_one2one ) Rat_ Lamb2 ( ortholog_one2one ) Rabbit_ LAMB2 ( ortholog_one2one ) |
| Ohnologs | LAMB4, LAMB1 |
| Paralogs | LAMC3, NTN4, LAMB1, LAMA3, LAMC1, ATRNL1, LAMA2, TMEFF2, ATRN, NTN1, NTN3, LAMC2, TMEFF1, LAMA1, AGRN, LAMB4, NTNG2, NTNG1, LAMA4, MEGF9, MEGF8, LAMB3, EGFLAM, LAMA5, NTN5, USH2A, HSPG2 |
| Tissue | NA |
| Tissue Specificity | Found in the basement membranes (major component). |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.038210(Rat);0.089011(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5XAU (X-ray 1.80A ) 7CEC (EM 3.90A ) |
| DBSNP | rs20563 rs2230157 rs20558 rs548688323 rs20559 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix, basement membrane. |
| Mouse PG classification | NA |
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