Gene Information
Gene NameFBXO3
OrganismHomo sapiens (Human)
Gene Length471
Protein NamesF-box only protein 3
Target Namef-box only protein 3
Target TypePreclinical target
Gene Age886 ( ENSG00000110429 )
Evolutionary StageEukaryota
AlphaFoldDBQ9UK99
Gene CardFBXO3
Uniprot IDQ9UK99
PfamPF04379; PF12937; PF09346
In ASDno
Allosteric Predictionno (-1.243704959)
Ortholog in AnimalsAlpaca_ FBXO3 ( ortholog_one2one )
Dog_ FBXO3 ( ortholog_one2one )
GuineaPig_ FBXO3 ( ortholog_one2one )
Macaque_ FBXO3 ( ortholog_one2one )
Mouse_ Fbxo3 ( ortholog_one2one )
Pig_ FBXO3 ( ortholog_one2one )
Rat_ Fbxo3 ( ortholog_one2one )
OhnologsNA
ParalogsPOLDIP2
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.04(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5HDW  (X-ray  2.00A 
DBSNP rs1402954 
Subcellular location [CC]Nucleus. Note=Colocalizes with PML at the peripheries of nuclear bodies.
Mouse PG classificationNA
click here to return to the previous page