| Gene Information | |
|---|---|
| Gene Name | ODF2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 829 |
| Protein Names | Outer dense fiber protein 2 (Cenexin) (Outer dense fiber of sperm tails protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000136811 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q5BJF6 |
| Gene Card | ODF2 |
| Uniprot ID | Q5BJF6 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.377992065) |
| Ortholog in Animals | Alpaca_ ODF2 ( ortholog_one2one ) Dog_ ODF2 ( ortholog_one2one ) GuineaPig_ ODF2 ( ortholog_one2one ) Macaque_ ODF2 ( ortholog_one2one ) Mouse_ Odf2 ( ortholog_one2one ) Pig_ ODF2 ( ortholog_one2one ) Rat_ Odf2 ( ortholog_one2one ) Rabbit_ ODF2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ODF2L |
| Tissue | testis |
| Tissue Specificity | Testis-specific (at protein level). Highly expressed in cytoplasm of step 2 round spermatids. Detected in the middle piece and extends to about half the principal piece of the sperm tails. {ECO:0000269|PubMed:10381817}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs16930426 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:14654843, ECO:0000269|PubMed:16966375}. Cell projection, cilium {ECO:0000250|UniProtKB:A3KGV1}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:23400999}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250|UniProtKB:A3KGV1}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:A3KGV1}. Note=Localized at the microtubule organizing centers in interphase and spindle poles in mitosis. Localized at the distal/subdistal appendages of mother centrioles. {ECO:0000250|UniProtKB:A3KGV1}. |
| Mouse PG classification | NA |
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