| Gene Information | |
|---|---|
| Gene Name | DDEF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1129 |
| Protein Names | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9ULH1 |
| Gene Card | ASAP1 |
| Uniprot ID | Q9ULH1 |
| Pfam | PF12796; PF01412; PF00169; PF14604 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.014963(Chimpanzee);0.028650(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2D1X (X-ray 1.90A ) 2DA0 (NMR - ) 2ED1 (NMR - ) 2RQT (NMR - ) 2RQU (NMR - ) |
| DBSNP | rs966185 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}. Note=Predominantly cytoplasmic. Partially membrane-associated. {ECO:0000250}. |
| Mouse PG classification | NA |
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