| Gene Information | |
|---|---|
| Gene Name | OCT4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 360 |
| Protein Names | POU domain, class 5, transcription factor 1 (Octamer-binding protein 3) (Oct-3) (Octamer-binding protein 4) (Oct-4) (Octamer-binding transcription factor 3) (OTF-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q01860 |
| Gene Card | POU5F1 |
| Uniprot ID | Q01860 |
| Pfam | PF00046; PF00157 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues. {ECO:0000269|PubMed:1408763, ECO:0000269|PubMed:7908264}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003605(Rat);0.034783(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6T90 (EM 3.05A ) 6YOV (EM 3.42A ) |
| DBSNP | rs1150767 rs1061120 |
| Subcellular location [CC] | Cytoplasm. Nucleus. Note=Expressed in a diffuse and slightly punctuate pattern. Colocalizes with MAPK8 and MAPK9 in the nucleus. {ECO:0000250|UniProtKB:P20263, ECO:0000269|PubMed:18191611, ECO:0000269|PubMed:19274063, ECO:0000269|PubMed:23024368}. |
| Mouse PG classification | NA |
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