| Gene Information | |
|---|---|
| Gene Name | ZMIZ1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1067 |
| Protein Names | Zinc finger MIZ domain-containing protein 1 (PIAS-like protein Zimp10) (Retinoic acid-induced protein 17) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000108175 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9ULJ6 |
| Gene Card | ZMIZ1 |
| Uniprot ID | Q9ULJ6 |
| Pfam | PF02891; PF18028 |
| In ASD | no |
| Allosteric Prediction | yes (0.142323787) |
| Ortholog in Animals | Alpaca_ ZMIZ1 ( ortholog_one2one ) Dog_ ZMIZ1 ( ortholog_one2one ) GuineaPig_ ZMIZ1 ( ortholog_one2one ) Macaque_ ZMIZ1 ( ortholog_one2one ) Mouse_ Zmiz1 ( ortholog_one2one ) Pig_ ZMIZ1 ( ortholog_one2one ) Rat_ Zmiz1 ( ortholog_one2one ) Rabbit_ ZMIZ1 ( ortholog_one2one ) |
| Ohnologs | ZMIZ2 |
| Paralogs | ZMIZ2, PIAS1, PIAS3, PIAS2, PIAS4 |
| Tissue | NA |
| Tissue Specificity | Expressed most abundantly in ovary and, at lower levels, in prostate, spleen and testis. Weak expression, if any, in thymus, small intestine, colon and peripheral blood leukocytes. {ECO:0000269|PubMed:14609956}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 5AIZ (X-ray 1.70A ) |
| DBSNP | rs1554817910 rs1589579476 rs1589579500 |
| Subcellular location [CC] | Nucleus, nucleoplasm {ECO:0000269|PubMed:14609956, ECO:0000269|PubMed:16777850}. Cytoplasm {ECO:0000269|PubMed:14609956}. Nucleus {ECO:0000269|PubMed:30639322}. Note=Enriched at replication foci throughout S phase. {ECO:0000269|PubMed:14609956}. |
| Mouse PG classification | NA |
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