| Gene Information | |
|---|---|
| Gene Name | CLDN17 |
| Organism | Homo sapiens (Human) |
| Gene Length | 224 |
| Protein Names | Claudin-17 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000156282 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P56750 |
| Gene Card | CLDN17 |
| Uniprot ID | P56750 |
| Pfam | PF00822 |
| In ASD | no |
| Allosteric Prediction | no (-1.201833618) |
| Ortholog in Animals | Alpaca_ CLDN17 ( ortholog_one2one ) Dog_ CLDN17 ( ortholog_one2one ) GuineaPig_ CLDN17 ( ortholog_one2one ) Mouse_ Cldn17 ( ortholog_one2one ) Pig_ CLDN17 ( ortholog_one2one ) Rat_ Cldn17 ( ortholog_one2one ) Rabbit_ CLDN17 ( ortholog_one2one ) |
| Ohnologs | CLDN2, CLDN20 |
| Paralogs | CLDN1, CLDN5, CLDN8, CLDN3, CLDN20, CLDN11, CLDN14, CLDN18, CLDN7, CLDN10, CLDN9, CLDN24, CLDN22, CLDN23, CLDN4, CLDN15, CLDN19, CLDN34, CLDN2, CLDN25, CLDN16, CLDN6 |
| Tissue | NA |
| Tissue Specificity | In the kidney, expressed in the proximal tubule and in the Henle's loop. In the distal convoluted tubule, not expressed in all tubules. Not detected in the collecting duct (at protein level). {ECO:0000269|PubMed:22402829}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35531957 |
| Subcellular location [CC] | Cell junction, tight junction {ECO:0000269|PubMed:22402829}. Cell membrane {ECO:0000269|PubMed:20375010}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |