| Gene Information | |
|---|---|
| Gene Name | GSPT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 499 |
| Protein Names | Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Eukaryotic peptide chain release factor subunit 3a) (eRF3a) (G1 to S phase transition protein 1 homolog) |
| Target Name | eukaryotic peptide chain release factor gtp-binding subunit erf3a |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000103342 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P15170 |
| Gene Card | GSPT1 |
| Uniprot ID | P15170 |
| Pfam | PF00009; PF03144; PF03143 |
| In ASD | no |
| Allosteric Prediction | no (-0.30929962) |
| Ortholog in Animals | Alpaca_ GSPT1 ( ortholog_one2one ) Dog_ GSPT1 ( ortholog_one2one ) GuineaPig_ GSPT1 ( ortholog_one2one ) Macaque_ GSPT1 ( ortholog_one2one ) Mouse_ Gspt1 ( ortholog_one2one ) Pig_ GSPT1 ( ortholog_one2one ) Rat_ Gspt1 ( ortholog_one2one ) Rabbit_ GSPT1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | EFTUD2, EIF2S3, EIF2S3B, GTPBP1, GUF1, EIF5B, MTIF2, EEF2, EFL1, GSPT2, EEFSEC, EEF1A1, EEF1A2, HBS1L, GTPBP2, GFM2, GFM1, TUFM |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001217(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3E1Y (X-ray 3.80A ) 3J5Y (EM 9.70A ) 3KUI (X-ray 2.30A ) 4D61 (EM 9.00A ) 5HXB (X-ray 3.60A ) 5LZT (EM 3.65A ) 6XK9 (X-ray 3.64A ) |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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