| Gene Information | |
|---|---|
| Gene Name | OAT4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 550 |
| Protein Names | Solute carrier family 22 member 11 (Organic anion transporter 4) (OAT4) (Organic anion:dicarboxylate exchanger OAT4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9NSA0 |
| Gene Card | SLC22A11 |
| Uniprot ID | Q9NSA0 |
| Pfam | PF00083 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in placental trophoblasts, syncytiotrophoblast and cytotrophoblast (PubMed:10660625, PubMed:12409283, PubMed:26277985). Also located in the proximal tubules in kidneys (PubMed:10660625, PubMed:15037815, PubMed:26277985). {ECO:0000269|PubMed:10660625, ECO:0000269|PubMed:12409283, ECO:0000269|PubMed:15037815, ECO:0000269|PubMed:26277985}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12785832 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:15291761, ECO:0000269|PubMed:15576633}; Multi-pass membrane protein {ECO:0000269|PubMed:15291761, ECO:0000269|PubMed:15576633}. Apical cell membrane {ECO:0000269|PubMed:15037815}; Multi-pass membrane protein {ECO:0000269|PubMed:15291761, ECO:0000269|PubMed:15576633}. Basal cell membrane {ECO:0000269|PubMed:12409283}; Multi-pass membrane protein {ECO:0000269|PubMed:15291761, ECO:0000269|PubMed:15576633}. Note=Expressed at the apical membrane of the proximal tubule epithelial cells (PubMed:15037815). Expressed at the basal membrane of the syncytiotrophoblast (PubMed:12409283). {ECO:0000269|PubMed:12409283, ECO:0000269|PubMed:15037815}. |
| Mouse PG classification | NA |
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