| Gene Information | |
|---|---|
| Gene Name | OAS3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1087 |
| Protein Names | 2'-5'-oligoadenylate synthase 3 ((2-5')oligo(A) synthase 3) (2-5A synthase 3) (EC 2.7.7.84) (p100 OAS) (p100OAS) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000111331 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9Y6K5 |
| Gene Card | OAS3 |
| Uniprot ID | Q9Y6K5 |
| Pfam | PF01909; PF10421 |
| In ASD | no |
| Allosteric Prediction | no (-0.872477484) |
| Ortholog in Animals | Alpaca_ OAS3 ( ortholog_one2one ) Dog_ OAS3 ( ortholog_one2one ) GuineaPig_ OAS3 ( ortholog_one2one ) Macaque_ OAS3 ( ortholog_one2one ) Mouse_ Oas3 ( ortholog_one2one ) Rat_ Oas3 ( ortholog_one2one ) Rabbit_ OAS3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | OAS2, OAS1, OASL |
| Tissue | NA |
| Tissue Specificity | Present at high level in placenta trophoblast. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4S3N (X-ray 2.00A ) |
| DBSNP | rs1859330 rs1859330 rs1859330 rs12819767 rs45519442 rs2285933 rs16942374 |
| Subcellular location [CC] | Cytoplasm. Nucleus. |
| Mouse PG classification | NA |
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