| Gene Information | |
|---|---|
| Gene Name | NYX |
| Organism | Homo sapiens (Human) |
| Gene Length | 481 |
| Protein Names | Nyctalopin |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000188937 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9GZU5 |
| Gene Card | NYX |
| Uniprot ID | Q9GZU5 |
| Pfam | PF13855; PF01462 |
| In ASD | no |
| Allosteric Prediction | no (-0.776754646) |
| Ortholog in Animals | Alpaca_ NYX ( ortholog_one2one ) Dog_ NYX ( ortholog_one2one ) GuineaPig_ NYX ( ortholog_one2one ) Macaque_ NYX ( ortholog_one2one ) Mouse_ Nyx ( ortholog_one2one ) Pig_ NYX ( ortholog_one2one ) Rat_ Nyx ( ortholog_one2one ) Rabbit_ NYX ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LRTM1, LRRTM3, BGN, LRRTM1, LRRC19, RTN4RL2, LRRC4B, PODN, LRRC15, FLRT2, FLRT1, LRRTM4, LRRC66, RTN4RL1, LRRC4, ASPN, PODNL1, FLRT3, DCN, GP1BA, RTN4R, LRRC4C |
| Tissue | NA |
| Tissue Specificity | Expressed in kidney and retina. Also at low levels in brain, testis and muscle. Within the retina, expressed in the inner segment of photoreceptors, outer and inner nuclear layers and the ganglion cell layer. {ECO:0000269|PubMed:11062471, ECO:0000269|PubMed:11062472}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs62637020 rs62637023 rs62637024 rs62637025 rs62637026 rs62637027 rs62637028 rs62637030 rs62637032 rs62637033 rs62637034 rs62637035 rs62637036 rs62637038 rs34169326 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix {ECO:0000250}. |
| Mouse PG classification | HPG |
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