| Gene Information | |
|---|---|
| Gene Name | NURR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 598 |
| Protein Names | Nuclear receptor subfamily 4 group A member 2 (Immediate-early response protein NOT) (Orphan nuclear receptor NURR1) (Transcriptionally-inducible nuclear receptor) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P43354 |
| Gene Card | NR4A2 |
| Uniprot ID | P43354 |
| Pfam | PF00104; PF00105 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in a number of cell lines of T-cell, B-cell and fibroblast origin. Strong expression in brain tissue. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1OVL (X-ray 2.20A ) 5Y41 (X-ray 2.05A ) 5YD6 (X-ray 2.34A ) 6DDA (X-ray 3.20A ) 6L6L (X-ray 2.78A ) 6L6Q (X-ray 2.60A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. Nucleus. Note=Mostly nuclear; oxidative stress promotes cytoplasmic localization. |
| Mouse PG classification | NA |
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