Gene Information
Gene NameNUPR1
OrganismHomo sapiens (Human)
Gene Length82
Protein NamesNuclear protein 1 (Candidate of metastasis 1) (Protein p8)
Target NameNA
Target TypeNA
Gene Age424 ( ENSG00000176046 )
Evolutionary StageEumetazoa
AlphaFoldDBO60356
Gene CardNUPR1
Uniprot IDO60356
PfamPF10195
In ASDno
Allosteric Predictionno (-1.251900634)
Ortholog in AnimalsAlpaca_ NUPR1 ( ortholog_one2one )
Dog_ NUPR1 ( ortholog_one2one )
GuineaPig_ NUPR1 ( ortholog_one2one )
Mouse_ Nupr1 ( ortholog_one2one )
Pig_ NUPR1 ( ortholog_one2one )
Rabbit_ NUPR1 ( ortholog_one2one )
OhnologsNA
ParalogsNUPR2
TissueNA
Tissue SpecificityWidely expressed, with high levels in liver, pancreas, prostate, ovary, colon, thyroid, spinal cord, trachea and adrenal gland, moderate levels in heart, placenta, lung, skeletal muscle, kidney, testis, small intestine, stomach and lymph node, and low levels in brain, spleen, thymus and bone marrow. Not detected in peripheral blood leukocytes. {ECO:0000269|PubMed:10092851}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:10092851, ECO:0000269|PubMed:16300740}. Cytoplasm {ECO:0000269|PubMed:16300740}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:16300740}.
Mouse PG classificationNA
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