| Gene Information | |
|---|---|
| Gene Name | NUP93 |
| Organism | Homo sapiens (Human) |
| Gene Length | 819 |
| Protein Names | Nuclear pore complex protein Nup93 (93 kDa nucleoporin) (Nucleoporin Nup93) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000102900 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8N1F7 |
| Gene Card | NUP93 |
| Uniprot ID | Q8N1F7 |
| Pfam | PF04097 |
| In ASD | no |
| Allosteric Prediction | yes (0.112007748) |
| Ortholog in Animals | Alpaca_ NUP93 ( ortholog_one2one ) Dog_ NUP93 ( ortholog_one2one ) GuineaPig_ NUP93 ( ortholog_one2one ) Macaque_ NUP93 ( ortholog_one2one ) Mouse_ Nup93 ( ortholog_one2one ) Pig_ NUP93 ( ortholog_one2one ) Rat_ Nup93 ( ortholog_one2one ) Rabbit_ NUP93 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.242828(Mouse);NULL(Rat);0.053333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5IJN (EM 21.40A ) 5IJO (EM 21.40A ) 7MW0 (X-ray 2.00A ) 7MW1 (X-ray 3.40A ) 7PER (EM 35.00A ) 7R5K (EM 12.00A ) |
| DBSNP | rs145146218 rs17853288 rs145473779 rs757674160 |
| Subcellular location [CC] | Nucleus membrane {ECO:0000250|UniProtKB:Q66HC5}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q66HC5}. Nucleus, nuclear pore complex {ECO:0000269|PubMed:12802065, ECO:0000269|PubMed:15229283, ECO:0000269|PubMed:9348540}. Nucleus envelope {ECO:0000269|PubMed:26878725, ECO:0000269|PubMed:9348540}. Note=Localizes at the nuclear basket and at or near the nuclear entry to the gated channel of the pore. {ECO:0000269|PubMed:9348540}. |
| Mouse PG classification | NA |
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