| Gene Information | |
|---|---|
| Gene Name | NUP58 |
| Organism | Homo sapiens (Human) |
| Gene Length | 599 |
| Protein Names | Nucleoporin p58/p45 (58 kDa nucleoporin) (Nucleoporin-like protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000139496 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9BVL2 |
| Gene Card | NUP58 |
| Uniprot ID | Q9BVL2 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.667148289) |
| Ortholog in Animals | Alpaca_ NUP58 ( ortholog_one2one ) Dog_ NUP58 ( ortholog_one2one ) GuineaPig_ NUP58 ( ortholog_one2one ) Macaque_ NUP58 ( ortholog_one2one ) Mouse_ Gm49336 ( ortholog_one2one ) Pig_ NUP58 ( ortholog_one2one ) Rat_ Nup58 ( ortholog_one2one ) Rabbit_ NUP58 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.087846(Mouse);NULL(Rat);0.082755(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4JO7 (X-ray 1.75A ) 4JO9 (X-ray 2.50A ) 4JQ5 (X-ray 2.20A ) 5IJN (EM 21.40A ) 5IJO (EM 21.40A ) 7PER (EM 35.00A ) 7R5K (EM 12.00A ) |
| DBSNP | rs11556093 rs12871608 |
| Subcellular location [CC] | Nucleus, nuclear pore complex {ECO:0000250|UniProtKB:P70581}. Nucleus membrane {ECO:0000250|UniProtKB:P70581}; Peripheral membrane protein {ECO:0000250|UniProtKB:P70581}; Cytoplasmic side {ECO:0000250|UniProtKB:P70581}. Nucleus membrane {ECO:0000250|UniProtKB:P70581}; Peripheral membrane protein {ECO:0000250|UniProtKB:P70581}; Nucleoplasmic side {ECO:0000250|UniProtKB:P70581}. Note=Biased towards cytoplasmic side. Central region of the nuclear pore complex, within the transporter. {ECO:0000250|UniProtKB:P70581}. |
| Mouse PG classification | NA |
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